Photodynamic antimicrobial chemotherapy (PACT) for the treatment of malaria, leishmaniasis and trypanosomiasis

A photodynamic effect occurs when photosensitiser molecules absorb light and dissipate the absorbed energy by transferring it to biological acceptors (usually oxygen), generating an excess of reactive species that are able to force cells into death pathways.Several tropical diseases present physiopathological aspects that are accessible to the appl

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Fundamental Frequency Variation of Neonatal Spontaneous Crying Predicts Language Acquisition in Preterm and Term Infants

Spontaneous cries of infants exhibit rich melodic features (i.e., time variation of fundamental frequency [F0]) even during the neonatal period, and the development of these characteristics might provide an essential base for later expressive prosody in language.However, little is known about the melodic features of spontaneous cries in preterm inf

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Prolidase deficiency, a rare inborn error of immunity, clinical phenotypes, immunological features, and proposed treatments in twins

Abstract Background Prolidase deficiency (PD) is an autosomal recessive inborn multisystemic disease caused by mutations in the PEPD gene encoding the enzyme prolidase D, leading to defects in turnover of proline-containing proteins, such as collagen.PD Control Board is categorized as a metabolic disease, but also as an inborn error of immunity.PD

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Morphometric characteristics of latitude parameters of the middle cranial fossa of mature age human depending on extreme type of skull structure

The study of the structure, shape and size of the skull and its individual structures is in great demand not only from the point of view of expansion of knowledge of craniology, but also modern practical Induction Range medicine.This is due to the rapid development of new methods for diagnosing pathological processes and the development of less tra

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